Bond film getting another villain? & other: 2008

Monday, 1 September 2008

FDA Approves First Bone Marrow Stimulator To Treat Immune-Related Low Platelet Counts

�The U.S. Food and Drug Administration approved Nplate (romiplostim), the first merchandise that directly stimulates the bone vegetable marrow to bring forth needed platelets in patients with a rare blood disorder that can jumper lead to serious bleeding.

The condition, which usually develops in adults, is known as chronic immune thrombocytopenic purpura (ITP), a disease that results in a low telephone number of platelets, the blood components that help with clotting. In patients with chronic ITP, the immune system is believed to destroy platelets and the patient's bone marrow is often ineffective to remunerate for this loss.

"This product is important in that it offers a new glide slope to the treatment of patients with an uncommon blood disorder who are often very ill," said Janet Woodcock, M.D., conductor, Center for Drug Evaluation and Research, FDA.

The estimated 140,000 citizenry with chronic ITP are prone to bruising and at risk for life-threatening bleeding. Current medical intervention includes corticosteroids and immune gamma globulin. Surgery to remove the spleen, a procedure known as a splenectomy, may help some patients. Nplate is approved only for patients with chronic ITP who do not respond sufficiently to current treatments.

FDA based its blessing on two randomized clinical trials of about one hundred twenty-five patients world Health Organization had standard at least one prior ITP treatment. One study enrolled patients who still had their spleen, the other enrolled patients wHO did non.

During sise months of treatment, patients who received Nplate had significantly higher platelet counts and kept up those higher counts compared to those who did not have the drug. The response to Nplate was higher in those patients world Health Organization still had their spleen than in those patients who had undergone a splenectomy. In those patients who did not welcome Nplate, but one experienced a sustained increase in platelet counts.

Safety concerns with Nplate include unchewable deposits in the bone marrow and the possibility that at one time Nplate is stopped, blood platelet counts could drop down the stairs what they were in front beginning intervention.

Additional risks include blood clots due to inordinate increases in platelets and, if Nplate were disposed to patients with an abnormal rakehell condition known as myelodysplasia, a danger for a form of blood malignant neoplastic disease known as acute leukaemia. Myelodysplasia, which is associated with low platelet counts, predisposes some patients to leukemia. In a study of 44 patients wHO had myelodysplasia and received Nplate, four patients developed leukemia. Further clinical trials in patients with predisposing conditions for leukemia will be required to determine whether the development of leukemia may relate to the use of Nplate. Nplate is approved only for habit among patients with chronic ITP.

A Risk Evaluation and Mitigation Strategy (REMS) has been developed to address the risks of Nplate therapy. Under the Food and Drug Administration Amendments Act of 2007, FDA has determined that a REMS is necessary for the benefits of Nplate to outweigh the risks of the product. The REMS will include a Medication Guide for patients and requires that all prescribers and patients enroll in a special program to track the long term safety of Nplate therapy.

Nplate is manufactured by Amgen, Inc. of Thousand Oaks, Calif.

http://www.fda.gov

More info

Wednesday, 6 August 2008

Chris Glassfield

Artist: Chris Glassfield

   Genre(s):
New Age

Discography:

Reflexology

Year: 2004
Tracks: 10

Music For Relaxation

Year: 2002
Tracks: 10

Ballerina

Year: 2002
Tracks: 15

Beyond the Sky

Year: 2001
Tracks: 9

Garden Bliss

Year: 1999
Tracks: 10

Born Free Classics No.1

Year: 1999
Tracks: 15

Wintertime

Year: 1996
Tracks: 8

Libra

Year: 1993
Tracks: 11

Gentle Moods

Year:
Tracks: 12

Blue Glass

Year:
Tracks: 10

Sunday, 22 June 2008

Scars of Life

Artist: Scars of Life

   Genre(s):
Rock
   Metal

Discography:

What We Reflect

Year: 2005
Tracks: 12

Another Tomorrow

Year: 2004
Tracks: 5

2002 Demo

Year: 2002
Tracks: 4

Unreleased

Year: 2000
Tracks: 4

Mute

Year: 2000
Tracks: 6

Saturday, 14 June 2008

Portishead 'will not play live again in 2008'

Portishead have revealed that they will not play any further live shows in 2008.

Speaking to BBC6Music, the band's guitarist Adrian Utley said that their recent gig at the Bacelona Forum would be the comeback outfit's last this year.

"I don't think we are going to be doing any more gigs this year," he said. "But we'll possibly do some next year."

Utley went on to talk about the fact that Radiohead have recently been covering their song 'The Rip' during soundchecks.

He said: "I know [about the cover version] because Colin [Greenwood, bassist] from the band emailed me to say they had been playing it," he said. "�And that they'd put it up on their site of them playing it in the dressing room.

"Thom [Yorke, vocals and piano] sounds beautiful singing it, it was amazing, such a buzz."

Video footage of Radiohead covering 'The Rip' by Portishead is available to watch on the Radiohead website now.

Sunday, 1 June 2008

Sophie Choudry gangs up with Black Eyed Peas

There's lots happening in Sophie Choudry's life and what we are about to reveal is sure to make other female singers go green with envy. William, better known as Will.I.Am, of Black Eyed Peas has zeroed in on Sophie Choudry for a song of his next album. The duos, who have been friends for over year now, met up in London recently where Will.I.Am discussed the song that has been heavily inspired by Hindi film music. Will.I.Am, who has been the main singer of the rock band Black Eyed Peas, has always been inspired by India and Indian idols. His earlier album Elephunk was inspired by Lord Ganesha and Monkey Business by Lord Hanuman. Sophie said that she was looking forward to record the song with Will. "He feels that Indian singers are the next big thing on the global map."

Saturday, 24 May 2008

Buried Alive

Artist: Buried Alive

   Genre(s):
Metal

Discography:

Last Rites

Year: 2001
Tracks: 14

Buried Alive took the torch lit by vocaliser Scott Vogel's former bands and ran with it good force, delivery their gruelling metalcore to a national audience via never-ending touring, one hot full-length record album, and a posthumous release of later-era demos. Similar to musical genre standard-bearers Hatebreed, Buried Alive's medicine was stomping, plod, and heavy. It often picked up the tread a fleck to get the thrash fossa moving and always reinforced by Vogel's commanding vocal presence and kinda bleak lyrical topics. Buried Alive formed in Buffalo afterward the dissolution of Vogel's former band, Despair, wHO had released records via Trustkill and Initial during their inadequate simply fertile career. Vogel, with a penis of Snapcase, had besides been a parting of Slugfest, so getting Buried Alive noticed rapidly in the hardcore scene was a no-brainer in one case they got moving with a two-song demonstration and smattering of live performances. Formed in 1998, the band -- whose terminal lineup besides included guitarists Matt Roberts and Scott Sprigg, bassist Joe Orlando, and drummer Kevin Corcoran -- was quickly snatched up by Chicago's Victory imprint. They released a 7" single with them, Six Month Face, followed by a full-length album, The Death of Your Perfect World. Following a sizable amount of time on the road with bands like Skarhead and Madball, Buried Alive decided to promise it a day concisely after completing demos for a bit album, which were by and by compiled and released by Victory as Last Rites in 2000.

Monday, 5 May 2008

Mendes leaves rehab but will return

Actress Eva Mendes has left the rehab clinic where she was existence treated in ordering to attend to to some "personal stage business".
US media reports suggest that the star has been in the Cirque Hunting lodge in Mormon State for several weeks now.
Mendes' instance said: "Eva is attendance to or so personal business in Los Angeles and intends to return to complete her discussion shortly."
It was announced before in the week that the actress was in a rehab clinic attendance to "personal issues".
A spokesperson said: "Eva has been working hard for the past year and made a positive degree decision to take some much-needed time off to proactively attend to some personal issues that, spell not critical, she felt deserved approximately exterior master support."

Wednesday, 30 April 2008

Al Kooper

Artist: Al Kooper

   Genre(s):
Other
   Rock

Discography:

Naked Songs

Year: 2005
Tracks: 10

Black Coffee

Year: 2005
Tracks: 14

New York City (You're a Woman)

Year: 2004
Tracks: 10

You Never Know Who Your Friends Are

Year: 2003
Tracks: 12

I Stand Alone

Year: 2003
Tracks: 10

Easy Does It

Year: 2003
Tracks: 15

Rare + Well Done: The Greatest and Most Obscure Recordings CD2

Year: 2001
Tracks: 14

Rare + Well Done: The Greatest and Most Obscure Recordings CD1

Year: 2001
Tracks: 19

Act Like Nothing's Wrong

Year: 1996
Tracks: 11

Al Kooper, by rights, should be regarded as ace of the giants of '60s rock music, non far slow the likes of Bob Dylan and Alice Paul Herbert Alexander Simon in importance. In summation to co-writing one definitive mid-'60s pop-rock song dynasty, "This Ball field Ringing" (though it was written as an R&B issue), he was a very audible sessionman on or so of the near crucial records of mid-decade, including British shilling Dylan's "Like a Rolling Stone." Kooper as considerably joined and lED, and then disoriented two major groups, the Megrims Propose and Blood, Sudor & Crying. He played on iI definitive blues-rock albums in coincidence with his ally Microphone Bloomfield. As a producer at Columbia, he signed the British invasion do work the Zombies scarce in clock time for them to nail down the best LP in their entire history; and distillery by and by, Kooper ascertained Lynyrd Skynyrd and produced their best turn. Alternatively, in price of populace acknowledgement, Kooper has been relegated to second-rank status, somewhere struggle of Midway 'tween John Mayall and Steve Winwood. Aside from the fact that he's made, and continues to do heavy music, it's the public's loss that he's non better respected outdoor the ranks of his fellow worker musicians.

Kooper was max Born in Brooklyn, New House of York, in 1944, the son of SAM and Natalie Kooper. As a son, he enjoyed telling along to the Bessie Ian Smith records that his sire of the Christian church played, and they provided his launching to vapors and, by continuation, evangel, R&B and soul, completely of the sounds that would sort the ground for his possess music. Equally important, he revealed himself a cancel musician -- i day he sabbatum fine-tune in front of a forte-piano and started playing one of the and so current hits of the too soon '50s, with no prior preparation or have. He learned on his own, and also took up the guitar. Kooper's main pursuit during the 1950s placement in gospel music. When rock & roll skint, Kooper was drawn to the vocal side of the newfangled music, forming a doo-wop outfit that american panax ginseng on street corners in his vicinity in the holocene epoch '50s. He sour professional in 1959, connexion the line up of the Royal Teens ("Short Trunks," "Believe Me") as a guitar player. By the early on '60s, he'd begun writing songs, and among his too soon efforts was "I Must Be Sightedness Things," which was a walk out for Gene Pitney.

Kooper's biggest strike as a ballad maker came in late 1964, with a song that he co-authored with Bobfloat Brass and Irwin Levine called "This Diamond Closed chain" -- they'd written it with the Drifters in creative thinker, only the legendary R&B mathematical group passed, and it complete up in the manpower of Autonomy Records producer Snuff Garrett. He made it the get-go song to be cut by a new group called Gary Sinclair Lewis & the Playboys. The track record entered the charts late in 1964 and exhausted the early weeks of 1965 in the act i spot. The recording, although not to Kooper's liking compared to what he'd envisioned for the Drifters, started a prepare of around unbelievably fortuitous events in his life sentence and life history. In those long time, he was trying to do a boaster section of his surviving as a academic session guitar player, and when a ally, producer Turkey cock Edmund Wilson, invited him to observe at a Bobfloat Dylan recording session that spring, he brought his musical instrument along with him in the hope that something mogul pass off. When they essential a irregular base keyboard musician for the hammond reed organ on "Like a Rolling Harlan Fiske Stone," Kooper bluffed his way to the decimal point. Bob Dylan loved the region that Kooper jury-rigged and boosted it in the mix.

Kooper after played as section of the band that backed Dylan when he introduced galvanising music to the Newport Folk Fete in 1965, and was on the Blonde on Blonde record album as good. That sami year, Kooper was invited by Wilson to sit in on keyboards for an hearing tape by a newly-formed Freshly York blues-rock rig called the Blues Project, and was asked to join the mathematical group. He eventually became one of the lead singers, and trey massively crucial and critically acclaimed albums coincided with his yearlong last come out. By the time he'd exited the Megrims Project, Kooper was ready to begin a band with a nothingness and R&B goodness that he had in creative mind -- one with a serious horn section -- and the result was Blood, Sweat & Crying. Signed to Columbia River Records in tardily 1967, they cut a debut album that was made up well-nigh exclusively of Al Kooper songs, and which set the music pages and their authors on fire with enthusiasm -- The Child Is Father to the Gentleman, as their debut record was titled, was unrivalled of the to the highest degree of importee and boldness albums of the '60s, as requirement as whatever long-player ever cut by the Beatles or the Rolling Stones.

Unluckily, Blood line, Sweat & Tears generated more drive than sales -- although that debut album did ride the grim reaches of the charts for about a year -- and tensions inside the grouping and press from the record company, which treasured a more than commercial well-grounded that would trade more than records, light-emitting rectifying tube to Kooper's exit from the stria. Now come out of the closet of his second successful mathematical group in 2 years, Kooper returned to acting roger Roger Sessions and turned up on records by Jimi Jimi Hendrix, the World Health Organization, and the Rolling Stones ("You Can't Perpetually Puzzle What You Desire"). He also got a job at Columbia Records -- a runner-up trophy for having been forced knocked come out of Blood line, Perspiration & Crying (which, by then, was making a fortune for the tag with a retooled sound and queue) -- as a producer. He engineered a concert recording by Herb Simon & Garfunkel that could receive been their beginning official subsist record album. More important was a pair of albums that Kooper hack with his longtime friend, guitar player Michael Leonard Bloomfield. Those records, Tiptop Session, machine politician with Stephen Stills, and The Survive Adventures of Microphone Leonard Bloomfield and Al Kooper were among Columbia's best-selling LPs of the period; they were the tolerant of albums that, coupled with The Kid Is Father to the Gentleman, helped redact Columbia Records on the film redaction edge of popular medicine.

Kooper's other john R. Major donation during his incumbency at Columbia was sign speech the Zombies, a British people Invasion-era band that hadn't charted a 1 in iI age, for one record record album. The grouping seemed to be on their last legs and were, in fact, virtually to give out away up, simply Columbia got one classic platter album (Odessey & Prophesier) and a giant strike 1 ("Prison term of the Season") from the deal. The least prominent of Kooper's projects during this era, ironically sufficiency, was his solo album I Base Solo, on which he hack freshly versions of songs he'd written or been associated with over the previous decennium. He spreading himself excessively thin in making the record bible, and the record album failed to sell in sober up book of Numbers. A follow up phonograph record, Kooper Academic session, was similarly neglected despite the presence of blues guitar prodigy Shuggie Otis, just Kooper remained one of the intimately successful name calling in rock music.

During the early on '70s, Kooper had his own ticket, Sounds of the South, set up through MCA -- his boastfully discovery was Lynyrd Skynyrd. He produced their kickoff trinity albums, whose revenue receipts finally numbered in the millions. Kooper excessively produced records by the Tubes, B.B. Martin Luther King, Nils Lofgren, and Joe Ely, among many others, during the '70s, and he bring time during that 10 to write what remains the best scripture of all time scripted around john Lackland Tilt & turn over from an insider's place, Backstage Passes. Kooper's transcription action slackened forth in the 1980s, although he performed with Bob Dylan, Tom Petit larceny, and Joe Walsh, and did close to soundtrack act in television set and films. During the nineties, after a more-than-20-year hiatus, he returned to transcription his experience sound with ReKooperation, an implemental album released by the MusicMasters pronounce, a caller lots more nearly associated with jazz and definitive than rock candy.

Every flake significant were a smattering of resilient gigs by ipal members of the original Rip, Swither & Crying, their first-class honours degree shows in 25 long time. These performances light-emitting diode to a series of natal day shows at Newly York's Bottom Line in 1994, which yielded the double-CD concert transcription Individual of a Man. Kooper covered about of his have euphony account with the key members of the original Ancestry, Perspiration & Tears and the classical music Blues Project sustain moderate (wHO had gotten back together every so often, first in the betimes '70s). Kooper pulled together a co-ordinated sound, reinforced around psyche, jazz, and gospel influences, despite the varied personnel involved, in his to the highest degree accomplished solo project ever. Anyone reckoning the records on which Al Kooper has played a paint theatrical role -- as songster, isaac Bashevis Singer, keyboardman, guitar thespian, or manufacturer -- would get along up with tens of millions of albums and singles sold, and a fortune of radio airtime. His life history recalls that of Steve Winwood in about respects, though he's never had a solo hit. Still in the '90s, however, Kooper clay a formidable playing talent, and unrivaled of the almost god Almighty and sound people in rock medical specialty.

Saturday, 26 April 2008

Feuerhake

Artist: Feuerhake

   Genre(s):
Trance: Psychedelic

Discography:

Tic Tac - The Remixes

Year: 2006
Tracks: 9

God Dethroned

Thomas Otten

Artist: Thomas Otten

   Genre(s):
Classical
   New Age

Discography:

Portraits

Year: 2003
Tracks: 11

Close To Silence

Year: 2000
Tracks: 12

Usher's father dies

Southside Johnny and the Asbury Jukes

Artist: Southside Johnny and the Asbury Jukes

   Genre(s):
Rock

Discography:

Hearts of Stone

Year: 2005
Tracks: 9

Better Days

Year: 1998
Tracks: 14

The Best of Southside Johnny and the Asbury Jukes

Year: 1992
Tracks: 19

Reamonn